POET-2 (ACE)

Breaking news: All Australian sites have discontinued involvement in the POET-2 trial.

This webpage will soon be deleted as a consequence of this.

Accelerated Treatment of endocarditis : the POET-2 trial.

This global trial follows-on from the widely quoted POET trial, but instead of an oral treatment arm, this trial has only intravenous antibiotics with the general principle of randomization to either conventional treatment duration versus abbreviated treatment duration in selected cases of left-sided endocarditis (Staphylococcal and Streptococcal variants)

POET-2 AHJ article via Europe PMC

This link leads to international protocol, with critical details in the 4 tables at end of article.

The 4 Australian sites (so far ) are:

The Prince Charles Hospital  Link to ieQ POET-2 page

Barwon (Geelong) Hospital

Fiona Stanley Hospital

Queen Elizabeth and Royal Adelaide Hospitals

If other sites are interested, please contact ieQ for details.