Molecular analysis of renal cell carcinoma metastasis

Field: Cancers, Kidney disease

Location: Ochsner Clinical School

Type of student:  Both types will be considered (i.e. you are flexible with your project/s)

Type of work: Chart reviews, Literature review, Statistical analysis, Wet lab work

Brief synopsis: Renal cell carcinoma (RCC) is a deadly and difficult-to-treat cancer. In one year in USA and Australia, approximately 66,000 new cases and 15,000 deaths from RCC occurred. RCC is a complex disease with widely varying prognosis. Metastatic RCC is incurable and fatal. Our hypothesis is that RCC and lymph node (LN) stromal cell interactions enhance tumorigenicity, metastasis, and drug resistance. Our goal for this project is to identify the molecular signals involved in tumor/LN stromal interaction and further examine their roles in tumor progression, metastasis, and chemotherapy resistance.

Time frame: Open time frame