Dr Iulia Oancea
Clinical Science Lead & Course Coordinator - Integrated Clinical Studies (MEDI7212)
Academy for Medical Education
+61 7 3343 2055
Iulia coordinates the Integrated Clinical Studies course offered in Semester 2 Year 2, which provides students with the opportunity to revise, extend, and integrate key Clinical Science, Public Health and Research concepts. Iulia also works in collaboration with the Clinical Science team to support the teaching and learning of students enrolled in the respective courses within Year 1 and Year 2 of the MD Program.
Book Chapter
Oancea, I. and Duley, J. A. (2008). Pharmacogenetics of thiopurines. Goodman and Gilman's the Pharmacological Basis of Therapeutics. (pp. xx-xx) edited by Laurence L. Brunton, Keith L. Parker, Donald K. Blumenthal and Iain L.O. Buxton.. New York, United States: McGraw-Hill Medical. doi: 10.1002/9780470015902.a0025152
Journal Articles
Alabbas, Saleh Y., Giri, Rabina, Oancea, Iulia, Davies, Julie, Schreibner, Veronika, Florin, Timothy H. and Begun, Jakob (2023). Gut inflammation and adaptive immunity amplify acetaminophen toxicity in bowel and liver. Journal of Gastroenterology and Hepatology, 38 (4), 609-618. doi: 10.1111/jgh.16102
Movva, Ramya, Murtaza, Nida, Giri, Rabina, Png, Chin Wen, Davies, Julie, Alabbas, Saleh, Oancea, Iulia, O'Cuiv, Páraic, Morrison, Mark, Begun, Jakob and Florin, Timothy H. (2022). Successful Manipulation of the Gut Microbiome to Treat Spontaneous and Induced Murine Models of Colitis. Gastro Hep Advances, 1 (3), 359-374. doi: 10.1016/j.gastha.2021.12.008
Sheng, Yong Hua, Giri, Rabina, Davies, Julie, Schreiber, Veronika, Alabbas, Saleh, Movva, Ramya, He, Yaowu, Wu, Andy, Hooper, John, McWhinney, Brett, Oancea, Iulia, Kijanka, Gregor, Hasnain, Sumaira, Lucke, Andrew J., Fairlie, David P., McGuckin, Michael A., Florin, Timothy H. and Begun, Jakob (2021). A nucleotide analog prevents colitis associated cancer via Β-catenin independently of inflammation and autophagy. Cellular and Molecular Gastroenterology and Hepatology, 11 (1), 33-53. doi: 10.1016/j.jcmgh.2020.05.012
Braunstein, Mark, Oancea, Iulia, Barry, Benjamin, Darlington, Sharon, Steel, Jim, Hansen, David, Battock, James, Cheung, Daniel, Gan, Gregory, Hooper, Benjamin, Lundin, Reilly, Nicol, Ducan, O'Brien, Joshua, Whittington, Scott, Willkinson, Chris and Wong, Tse Tse (2019). The development and electronic delivery of case-based learning using a fast healthcare interoperability resource system. JAMIA Open, 2 (4), 440-446. doi: 10.1093/jamiaopen/ooz055
Alabbas, Saleh Y, Begun, Jakob, Florin, Timothy H and Oancea, Iulia (2018). The role of IL-22 in the resolution of sterile and nonsterile inflammation. Clinical and Translational Immunology, 7 (4) e1017, e1017. doi: 10.1002/cti2.1017
Florin, Timothy, Movva, Ramya, Begun, Jakob, Duley, John, Oancea, Iulia and O Cuiv, Paraic (2017). Colonic thioguanine pro-drug: investigation of microbiome and novel host metabolism. Gut Microbes, 9 (2), 1-4. doi: 10.1080/19490976.2017.1387343
Sheng, Yonghua, Ng, Choa Ping, Lourie, Rohan, Shah, Esha T., He, Yaowu, Wong, Kuan Yua, Seim, Inge, Oancea, Iulia, Morais, Christudas, Jeffery, Penny L., Hooper, John, Gobe, Glenda C. and Mcguckin, Michael A. (2017). MUC13 overexpression in renal cell carcinoma plays a central role in tumor progression and drug resistance. International Journal of Cancer, 140 (10), 2351-2363. doi: 10.1002/ijc.30651
Movva, Ramya, Haywood, Alison, Khan, Sohil A., Florin, Timothy H. J. and Oancea, Iulia (2017). Critical assessment of thioguanine treatment for inflammatory bowel diseases: Is it time to rehabilitate this treatment?. Journal of Digestive Diseases, 18 (9), 529-536. doi: 10.1111/1751-2980.12536
Movva, Ramya, Lobb, Michael, Ó Cuív, Páraic, Florin, Timothy H.J., Duley, John A. and Oancea, Iulia (2016). Microbial metabolism of thiopurines: a method to measure thioguanine nucleotides. Journal of Microbiological Methods, 128, 102-107. doi: 10.1016/j.mimet.2016.07.017
Oancea, I., Movva, R., Das, I., Aguirre de Carcer, D., Schreiber, V., Yang, Y., Purdon, A., Harrington, B., Proctor, M., Wang, R., Sheng, Y., Lobb, M., Lourie, R., Cuiv, P.O., Duley, J.A., Begun, J. and Florin, T.H.J. (2016). Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism. Gut, 66 (1), 59-69. doi: 10.1136/gutjnl-2015-310874
Sheng, Y. H., He, Y., Hasnain, S. Z., Wang, R., Tong, H., Clarke, D. T., Lourie, R., Oancea, I., Wong, K. Y., Lumley, J. W., Florin, T. H., Sutton, P., Hooper, J. D., McMillan, N. A. and McGuckin, M. A. (2016). MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target. Oncogene, 36 (5), 700-713. doi: 10.1038/onc.2016.241
Wang, Ran, Hasnain, Sumaira Z., Tong, Hui, Das, Indrajit, Che-Hao Chen, Alice, Oancea, Iulia, Proctor, Martina, Florin, Timothy H., Eri, Rajaraman D. and McGuckin, Michael A. (2015). Neutralizing IL-23 is superior to blocking IL-17 in suppressing intestinal inflammation in a spontaneous murine colitis model. Inflammatory Bowel Diseases, 21 (5), 973-984. doi: 10.1097/MIB.0000000000000353
Pavlidis, Polychronis, Ansari, Azhar, Duley, John, Oancea, Iulia and Florin, Timothy (2014). Splitting a Therapeutic Dose of Thioguanine May Avoid Liver Toxicity and Be an Efficacious Treatment for Severe Inflammatory Bowel Disease: A 2-Center Observational Cohort Study. Inflammatory Bowel Diseases, 20 (12), 2239-2246. doi: 10.1097/MIB.0000000000000206
Speckmann, Bodo, Gerloff, Kirsten, Simms, Lisa, Oancea, Iulia, Shi, Wei, McGuckin, Michael A., Radford-Smith, Graham and Khanna, Kum Kum (2014). Selenoprotein S is a marker but not a regulator of endoplasmic reticulum stress in intestinal epithelial cells. Free Radical Biology and Medicine, 67, 265-277. doi: 10.1016/j.freeradbiomed.2013.11.001
Das, Indrajit, Png, Chin Wen, Oancea, Iulia, Hasnain, Sumaira Z., Lourie, Rohan, Proctor, Martina, Eri, Rajaraman D., Sheng, Yong, Crane, Denis I., Florin, Timothy H. and McGuckin, Michael A. (2013). Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins. Journal of Experimental Medicine, 210 (6), 1201-1216. doi: 10.1084/jem.20121268
Oancea, Iulia, Png, Chin Wen, Das, Indrajit, Lourie, Rohan, Winkler, Ingrid G., Eri, Rajaraman, Subramaniam, Nathan, Jinnah, H. A., McWhinney, Brett C., Levesque, Jean-Pierre, McGuckin, Michael A., Duley, John A. and Florin, Timothy H. J. (2013). A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity. Gut, 62 (4), 594-605. doi: 10.1136/gutjnl-2012-302274
van Asseldonk, Dirk P., Oancea, Iulia, Jharap, Bindia, Duley, John A. and Florin, Timothy H. J. (2012). Is thioguanine-associated sinusoidal obstruction syndrome avoidable? Lessons learned from 6-thioguanine treatment of inflammatory bowel disease and a mouse model. Revista da Associação Médica Brasileira, 58 (Supp. 1), S8-S13.
Zamzami, Mazin A., Price, Gareth R., Taylor, Robert W., Blakely, Emma L., Oancea, Iulia, Bowling, Francis and Duley, John A. (2011). Insights into N-calls of mitochondrial DNA sequencing using MitoChip v2.0. BMC Research Notes, 4 (1) 426, 1-8. doi: 10.1186/1756-0500-4-426
Eri, R. D., Adams, R. J., Tran, T. V., Tong. H., Das. I., Roche, D. K., Oancea, I., Png, C. W., Jeffery, P. L., Radford-Smith, G.L., Cook, M. C., Florin, T. H. and McGuckin, M. A. (2011). An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity. Mucosal Immunology, 4 (3), 354-364. doi: 10.1038/mi.2010.74
Conference Papers
Aland, Claire, Oancea, Iulia, Midwinter, Mark, Pillai, Suja, Manchadi, Mary-Louise, Reichelt, Melissa and Wu, Sherry (2022). Using action learning to develop a model for inclusive teaching in a COVID-split cohort. 26th Annual International Association for Medical Science Educators, Denver, CO, United States, 4-7 June 2022.
Oancea, Iulia, Shepherd, Nicole, Berry, Benjamin and Barber, Liz (2021). Meaningful integration of medical disciplines into a capstone pre-clinical course. ANZAHPE, Online, 6-14 July 2021.
Li, Joan, Reddy, Venkat, Steele, Megan, Forster, Ashlee, Oancea, Ilulia, Midwinter, Mark, Aland, Claire, Pillai, Suja, Simpson, Peter, Babri, Saleem and Barry, Ben (2020). Designing retrospective analysis of examination items for medical students in clinical science categorisation by Bloom’s Taxonomy, clinical relevance and student perceptions. ANZAHPE2020, Melbourne, VIC Australia, 12-15 July 2020.
Barry, Benjamin, Braunstein, Mark, Oancea, Iulia, Darlington, Sharon, Steel, Jim and Hansen, David (2020). Digital disruption: student and tutor reactions to an electronic medical record to support case based learning in medicine. ANZAHPE 2020 Conference, Melbourne, VIC, Australia, 12-15 July 2020. Melbourne, VIC Australia: Australian & New Zealand Association for Health Professional Educators.
Barry, Benjamin, Lewis, Peter, Braunstein, Mark, Cottrell, Neil, Mandrusiak, Allison, Jauncey-Cooke, Jacqueline, Darlington, Sharon, Oancea, Iulia, Sullivan, Claire, Dobbins, Chelsea, Steel, Jim and Hansen, David (2020). Enabling interprofessional education via a new teaching tool based on an electronic medical record. ANZAHPE 2020 Conference, Melbourne, VIC, Australia, 12-15 July 2020. Melbourne, VIC, Australia: Australian & New Zealand Association for Health Professional Educators.
Sheng, Yong H., Giri, Rabina, Davies, Julie, Schreiber, Veronika, Alabbas, Saleh Y., He, Yaowu, Wu, Andy, Hooper, John, Oancea, Iulia, Kijanka, Gregor, Hasnain, Sumaira Z., McGuckin, Michael, Florin, Timothy H. and Begun, Jakob (2020). Thioguanine inhibits colorectal tumorigenesis via β-catenin signalling in intestinal epithelial cells independently of immunosuppression or autophagy. DDW 2020, Online, 2-5 May 2020. Philadelphia, PA United States: Elsevier . doi: 10.1016/s0016-5085(20)30856-8
Oancea, Iulia, Shepherd, Nicole, Barry, Benjamin, Barber, Elizabeth and Hill, Peter (2020). Evaluation of the integration of public health, research and clinical science into a single capstone course. ANZAHPE 2020 Conference, Melbourne, VIC Australia, 12-15 July 2020. Melbourne, VIC Australia: Australian & New Zealand Association for Health Professional Educators.
Darlington, Sharon, Oancea, Iulia, Barry, Benjamin K., Shepherd, Nicole, Mukandi, Bryan, Winch, Sarah and Wozniak, Helen (2019). Discriminative capacity of a rubric assessment of ethical reasoning and clinical reasoning in case-based learning tutorials. ANZAHPE 2019 Conference, Canberra, 1-4 July 2019.
Braunstein, Mark, Barry, Benjamin K., Oancea, Iulia, Steel, Jim, Darlington, Sharon and Hansen, David (2019). Building digital literacy of medical students by embedding teaching cases in an electronic medical record. ANZAHPE 2019 Conference, Canberra, Australia, 1-4 July 2019. Canberra, ACT Australia: Australian & New Zealand Association for Health Professional Educators.
Simerska, Pavla , Benjamin K. Barry, Oancea, Iulia , Aland, Claire , Midwinter, Mark , Pillai, Suja and Hawkins, Nicholas J. (2019). Does student performance on short answer questions vary from that on single best answer questions?. ANZAHPE 2019 Conference, Canberra, ACT, Australia, 1-4 July 2019. Australian & New Zealand Association for Health Professional Educators.
Barry, Benjamin K., Shepherd, Nicole, Darlington, Sharon, Mukandi, Bryan, Winch, Sarah, Wozniak, Helen and Oancea, Iulia (2019). Student and tutor evaluations of the integration of medical ethics in case-based learning discussions. ANZAHPE 2019 Conference, Canberra, ACT Australia, 1-4 July 2019. Canberra, ACT Australia: Australian & New Zealand Association for Health Professional Educators.
Oancea, Iulia, Barry, Benjamin K., Simerska, Pavla, Aland, Claire, Midwinter, Mark, Pillai, Suja and Hawkins, Nicholas (2019). Is an image worth a thousand words in the medical program exams?. ANZAHPE 2019 Conference, Canberra, ACT, Australia, 1-4 July 2019. Australian & New Zealand Association for Health Professional Educators.
Barry, Benjamin K., Simerska, Pavla, Aland, Claire, Midwinter, Mark, Hawkins, Nicholas, Pillai, Suja and Oancea, Iulia (2019). Does the context of an examination influence student performance in anatomy and pathology disciplines for clinical science courses in a medical program?. ANZAHPE 2019 Conference, Canberra, Australia, 1-4 July 2019.
Darlington, Sharon, Smith, Tammy and Oancea, Iulia (2019). Medical student attendance at lectures: is there a correlation with performance on assessment?. Australian and New Zealand Association for Health Professional Educators, Canberra, ACT Australia, 1-4 July 2019.
Barry, Benjamin K., Shepherd, Nicole, Darlington, Sharon, Mukandi, Bryan, Winch, Sarah, Wozniak, Helen and Oancea, Iulia (2019). Student and tutor evaluations of the integration of medical ethics in case-based learning discussions.. ANZAHPE 2019 Conference, Canberra, ACT, Australia, 1-4 July 2019. Canberra, ACT Australia: Australian & New Zealand Association for Health Professional Educators.
Shepherd, Nicole, Oancea, Iulia, Barry, Bem and Darlington, Sharon (2019). Student perceptions of learning about medical ethics in clinical case-based tutorials. Australasian Association of Bioethics and Health Law, Dunedin, New Zealand, 21-23 November 2019.
Alabbas, Saleh, Movva, Ramya, Begun, Jakob, Florin, Timothy and Oancea, Iulia (2019). On the role of inflammation in acute paracetamol injury. International Liver Congress, Vienna Austria, 10-14 April 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/S0618-8278(19)30823-0
Oancea, Iulia, Darlington, Sharon , Ward, Kym and Smith, Tammy (2018). Student engagement with lecture material: is there such a thing as too much flexibility?. Australian & New Zealand Association for Health Professional Educators 2018 Conference, Hobart, Australia, 1-4 July 2018.
Darlington, Sharon, Green, Louise, Smith, Tammy and Oancea, Iulia (2018). Symposium - Case-based Learning: Sustaining deep learning in the increasingly crowded curriculum. Australian & New Zealand Association for Health Professional Educators 2018 Conference, Hobart, TAS Australia, 1-4 July, 2018.
Oancea, Iulia, Shepherd, Nicole, Darlington, Sharon, Winch, Sarah and Barry, Ben (2018). Distributed assessment of medical ethics in case discussions facilitated by a large team of casual clinical tutors. ANZAHPE 2018 Conference, Hobart, TAS, Australia, 1-4 July 2018. Renmark, SA, Australia: Australian & New Zealand Association for Health Professional Educators.
Alabbas, S. Y., Mowa, R., Purdon, A. S., Begun, J., Florin, T. H. and Oancea, I. (2017). Subsets of innate lymphoid cells in acute liver injury. Australian Gastroenterology Week: Precision Medicine in Gastroenterology, Gold Coast, Queensland, 20-22 August 2017. HOBOKEN: Wiley-Blackwell.
Movva, R., Oancea, I., Png, C. W., Purdon, A. S., Alabbas, S. Y., Cuiv, P. O. and Florin, T. H. J. (2017). An antibiotic cocktail that results in a dysbiotic microbiome improves spontaneous colitis in the Winnie mouse. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, Gold Coast, QLD Australia, 20–22 August 2017. Richmond, VIC Australia: Wiley.
Movva, Ramya, Purdon, Amy S., Alabbas, Saleh Y., Cuiv, Paraic O., Florin, Timothy H. and Oancea, Iulia (2017). Cecal Microbiota Directly Affect Colitis Development in a Mouse Model of Induced Colitis. Digestive Disease Week, Chicago Il United States, 6-9 May 2017. Maryland Heights, MO United States: W.B. Saunders Co.. doi: 10.1016/S0016-5085(17)33346-2
Oancea, Iulia, Das, Indrajit D., de Carcer, Daniel Aguirre, Schreiber, Veronika, Wang, Ran, Sheng, Yong, Movva, Ramya, Cuiv, Paraic O, Duley, John, Begun, Jakob and Florin, Timothy H. (2016). 971d Colonic microbiota can promote rapid improvement of murine colitis by thioguanine independently of T-lymphocytes and host metabolism. Digestive Disease Week 2016, San Diego, CA USA, 21-24 May 2016. Philadelphia, PA USA: Elsevier. doi: 10.1016/s0016-5085(16)30737-5
Oancea, I., Das, I., de Carcer, D. Aguirre, Movva, R., Schreiber, V., Yang, Y., Proctor, M., Wang, R., Sheng, Y., Lobb, M., Cuiv, P. O., Duley, J. A., Begun, J. and Florin, T. H. J. (2016). Bacterial activation of thioguanine results in lymphocyte independent improvement in murine colitis. 11th Congress of ECCO - European Crohn’s and Colitis Organisation, Amsterdam, Netherlands, 16-19 March 2016. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjw019.177
Jose, Beulah, Lourie, Rohan, Schreiber, Veronika, Florin, Timothy H., Oancea, Iulia and Begun, Jakob (2016). Thiopurine Mediated Chemoprevention of Colitis-Associated Colorectal Dysplasia. 57th Annual Meeting and Residents Fellow Conference of the Society for Surgery of the Alimentary Tract (SSAT) / 52nd Annual Meeting on Digestive Disease Week (DDW) / Meeting of the American Gastroenterological Association (AGA57th Annual Meeting and Residents Fellow Conference of the Society for Surgery of the Alimentary Tract (SSAT) / 52nd Annual Meeting on Digestive Disease Week (DDW) / Meeting of the American-Gastroenterological-Association (AGA), San Diego, CA United States, 21-24 May 2016. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(16)33291-7
Oancea, Iulia, Barbier, Valerie, Chee, David, Lourie, Rohan, Movva, Ramya, Proctor, Martina A., Begun, Jakob, Magnani, John L., Florin, Timothy H. and Winkler, Ingrid (2016). Alleviation of Acute Drug-Induced Liver Injury Following Acetaminophen Overdose by Therapeutic Blockade of E-Selectin in Preclinical Mouse Model. 57th Annual Meeting and Residents Fellow Conference of the Society for Surgery of the Alimentary Tract (SSAT) / 52nd Annual Meeting on Digestive Disease Week (DDW) / Meeting of the American-Gastroenterological-Association (AGA), San Diego, CA United States, 21-24 May 2016. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(16)33483-7
Hasnain, S. Z., Taylor, S., Wang, R., Chen, A., Oancea, I, Das, I, Tong, H., Florin, T., Serisier, D., Coulson, B., Mcauley, J., Lourie, R., Phipps, S. and Mcguckin, M. (2016). Unravelling a novel mechanism by which cytokines induce ER stress to halt viral protein synthesis in mucosal epithelial cells. International Congress of Immunology (ICI), Melbourne, Australia, Aug 21-26, 2016. Weinheim, Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi: 10.1002/eji.201670200
Sheng, Yong H., He, Yaowu, Hasnain, Sumaira Z., Wang, Ran, Tong, Hui, Clarke, Daniel T., Lourie, Rohan, Oancea, Lulia, Wong, Kuanyau, Lumley, John W., Florin, Timothy H., Sutton, Philip, Hooper, John. D., Mcmillan, Nigel A. and Mcguckin, Michael A. (2016). MUC13 protects colorectal cancer cells from death by activating the NF-Kb pathway and is a potential therapeutic target. AACR 107th Annual Meeting on Bioinformatics and Systems Biology, New Orleans, Los Angeles, 16-20 April 2016 . Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2016-3564
Pavlidis, P., Ansari, A., Duley, J., Oancea, I. and Florin, T. (2014). Splitting the normal daily dose of thioguanine may be efficacious treatment for inflammatory bowel diesease and avoid hepatic toxicity. British Society of Gastroenterology Annual General Meeting, Manchester Central, United Kingdom, 16 - 19 June 2014. London, United Kingdom: B M J Group. doi: 10.1136/gutjnl-2014-307263.353
De Carcer, D. Aguirre, Oancea, I., Das, I., Mcguckin, M., Duley, J., Morrison, M. and Florin, T. (2011). Microbiome shifts with 6-thioguanine provide insights about IBD and its treatment. Australian Gastroenterology Week 2011, South Bank, QLD, Australia, 12–15 September 2011. MALDEN: WILEY-BLACKWELL. doi: 10.1111/j.1440-1746.2011.06820.x
Oancea, Iulia, Eri, Rajaraman D., McGuckin, Michael A., Duley, John A. and Florin, Timothy H. (2009). The effect of thiopurine on leukocytes in a C57BL/6 mouse model. *, *, *. Maryland Heights, MO, United States: W.B. Saunders Co..
Thesis
Iulia Oancea (2011). Improving Patient Outcomes Through Better Understanding of Thiopurine Metabolism. PhD Thesis, School of Medicine, The University of Queensland.